L-methamphetamine

L-Methamphetamine is a stereoisomer of methamphetamine, a powerful stimulant drug that affects the central nervous system. Unlike its more well-known isomer, D-methamphetamine, L-methamphetamine is not typically used recreationally due to its primarily peripheral effects and lack of central nervous system activity.

Chemistry

L-Methamphetamine is a member of the phenethylamine and amphetamine chemical classes. It is a chiral compound, meaning it exists in two forms that are mirror images of each other, known as enantiomers. The other enantiomer, D-methamphetamine, is the more commonly known and used form of the drug.

Pharmacology

L-Methamphetamine acts primarily as a vasoconstrictor and bronchodilator, constricting blood vessels and opening up airways in the lungs. This makes it useful in over-the-counter medications for nasal and chest congestion. Unlike D-methamphetamine, it does not have significant psychostimulant effects, as it does not significantly enter the central nervous system.

Medical Use

In the United States, L-methamphetamine is the active ingredient in the over-the-counter nasal decongestant Vicks VapoInhaler. It is also used in some over-the-counter asthma inhalers. It is considered safe for use in these applications, although it can cause side effects such as increased heart rate and blood pressure.

Legal Status

In the United States, L-methamphetamine is classified as a Schedule V controlled substance when sold over-the-counter in nasal decongestants. This is the least restrictive classification, indicating a low potential for abuse. However, it is illegal to manufacture or distribute L-methamphetamine for any other purpose.

See Also

• Methamphetamine
• Stereochemistry
• Phenethylamine
• Amphetamine