LP-211

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LP-211_structure.png

LP-211 is a synthetic compound that acts as a selective agonist for the 5-HT7 receptor. It has been primarily used in scientific research to investigate the role of the 5-HT7 receptor in various physiological and neurological processes.

Chemical Properties[edit | edit source]

LP-211 is a member of the class of compounds known as tryptamines. It has a molecular formula of C_20H_21N_3O and a molecular weight of 319.40 g/mol. The compound is characterized by its high affinity and selectivity for the 5-HT7 receptor, making it a valuable tool in neuropharmacological studies.

Pharmacology[edit | edit source]

The primary action of LP-211 is its agonistic effect on the 5-HT7 receptor, a subtype of the serotonin receptor family. The 5-HT7 receptor is involved in the regulation of various neurological processes, including circadian rhythm, mood, and cognition. Activation of this receptor by LP-211 has been shown to influence these processes, making it a subject of interest in the study of neuropsychiatric disorders such as depression, anxiety, and schizophrenia.

Research Applications[edit | edit source]

LP-211 has been utilized in various preclinical studies to explore the therapeutic potential of 5-HT7 receptor modulation. Research has indicated that LP-211 may have potential benefits in the treatment of sleep disorders, cognitive dysfunction, and mood disorders. Additionally, studies have investigated its role in neuroplasticity and neuroprotection, suggesting that LP-211 could be beneficial in conditions such as Alzheimer's disease and Parkinson's disease.

Safety and Toxicology[edit | edit source]

As with many research chemicals, the safety profile of LP-211 is not fully established. Preliminary studies suggest that it has a relatively low toxicity, but comprehensive toxicological data are lacking. Researchers using LP-211 are advised to follow standard safety protocols and conduct thorough risk assessments.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]


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Contributors: Prab R. Tumpati, MD