LY-393558

From WikiMD's Wellness Encyclopedia

LY-393558 is a drug that is used in scientific research. It is a potent and selective inhibitor of the enzyme glycogen synthase kinase 3 (GSK-3). LY-393558 has been shown to have neuroprotective effects in animal studies, and it is being investigated for potential use in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Mechanism of Action[edit | edit source]

LY-393558 works by inhibiting the enzyme GSK-3. This enzyme is involved in a number of cellular processes, including the regulation of glycogen metabolism, cell division, and cell differentiation. By inhibiting GSK-3, LY-393558 can potentially alter these processes and have a protective effect on neurons.

Potential Therapeutic Uses[edit | edit source]

Research has suggested that LY-393558 may have potential therapeutic uses in the treatment of neurodegenerative diseases. In animal studies, the drug has been shown to have neuroprotective effects, potentially slowing the progression of diseases such as Alzheimer's and Parkinson's. However, further research is needed to confirm these findings and determine the safety and efficacy of LY-393558 in humans.

Side Effects and Safety[edit | edit source]

As with any drug, LY-393558 has the potential to cause side effects. These can include nausea, vomiting, diarrhea, and dizziness. In addition, because LY-393558 is an inhibitor of GSK-3, it has the potential to interfere with normal cellular processes and cause unwanted effects. Therefore, the safety of LY-393558 is a key area of ongoing research.

See Also[edit | edit source]

LY-393558 Resources
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Contributors: Prab R. Tumpati, MD