LY-503,430
LY-503,430 is a drug that was developed by Eli Lilly, a multinational pharmaceutical company. It is an ampakine compound, which means it is a type of drug that modulates glutamate neurotransmission. Specifically, LY-503,430 enhances the function of the AMPA receptor, a type of glutamate receptor, in the brain. This drug has been studied for its potential use in the treatment of neurodegenerative diseases and cognitive disorders.
History[edit | edit source]
LY-503,430 was first synthesized and studied by researchers at Eli Lilly. The development of this drug is part of a larger effort to create effective treatments for neurodegenerative diseases and cognitive disorders.
Mechanism of Action[edit | edit source]
LY-503,430 is an ampakine, a class of drugs that modulate glutamate neurotransmission. Glutamate is the most abundant excitatory neurotransmitter in the brain, and it plays a crucial role in neural communication, memory formation, and learning. LY-503,430 enhances the function of the AMPA receptor, a type of glutamate receptor. By enhancing AMPA receptor function, LY-503,430 can increase glutamate neurotransmission and potentially improve cognitive function.
Potential Therapeutic Uses[edit | edit source]
Research has suggested that LY-503,430 may have potential therapeutic uses in the treatment of neurodegenerative diseases and cognitive disorders. These conditions are often characterized by impaired glutamate neurotransmission, and by enhancing AMPA receptor function, LY-503,430 may be able to alleviate some of these impairments.
See Also[edit | edit source]
- Eli Lilly and Company
- Ampakine
- Glutamate
- AMPA receptor
- Neurodegenerative diseases
- Cognitive disorders
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Contributors: Prab R. Tumpati, MD
