LY-503430
LY-503430 is an ampakine compound which acts as a positive allosteric modulator of the AMPA receptor. It has been investigated for its potential use in the treatment of schizophrenia, Alzheimer's disease, and attention deficit hyperactivity disorder (ADHD).
Pharmacology[edit | edit source]
LY-503430 is a potent and selective AMPA receptor potentiator. It enhances AMPA receptor-mediated synaptic responses in vitro and in vivo. The compound has been shown to improve cognitive function in animal models of schizophrenia and Alzheimer's disease.
Clinical Trials[edit | edit source]
LY-503430 has undergone Phase I clinical trials for the treatment of schizophrenia and Alzheimer's disease. The results of these trials have not been published.
Potential Therapeutic Uses[edit | edit source]
LY-503430 has potential therapeutic uses in the treatment of cognitive disorders such as schizophrenia, Alzheimer's disease, and ADHD. It may also have potential uses in the treatment of other neurological disorders such as Parkinson's disease and Huntington's disease.
See Also[edit | edit source]
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