Lamina cribrosa sclerae

Lamina cribrosa sclerae is a part of the eye anatomy, specifically located in the sclera, the white outer layer of the eye. It is a sieve-like structure through which the retinal ganglion cell axons exit the eye to form the optic nerve.

Structure

The lamina cribrosa sclerae is a circular, sieve-like region of the sclera, located at the back of the eye where the optic nerve exits. It is composed of connective tissue and is perforated by numerous small openings, through which the axons of the retinal ganglion cells pass. These openings are arranged in a radial pattern, with the largest openings located in the center and the smallest at the periphery.

Function

The primary function of the lamina cribrosa sclerae is to provide a pathway for the axons of the retinal ganglion cells to exit the eye and form the optic nerve. It also plays a role in supporting the optic nerve and maintaining the shape of the eye.

Clinical significance

Damage to the lamina cribrosa sclerae can lead to a number of vision-related problems. It is particularly vulnerable to changes in intraocular pressure, which can lead to glaucoma, a condition characterized by damage to the optic nerve and loss of vision. Studies have shown that the structure and thickness of the lamina cribrosa sclerae can be altered in glaucoma, which can contribute to the progression of the disease.

See also

• Sclera
• Optic nerve
• Glaucoma