Levalbuterol
Levalbuterol - a short acting sympathomimetic beta 2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol binds to beta 2 adrenergic receptors in bronchial smooth muscle and activates intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (atp) to cyclic 3',5' adenosine monophosphate (camp).
Mechanism of action[edit | edit source]
Increased camp levels lead to the activation of protein kinase a, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation of bronchial smooth muscles. The increased camp concentrations also inhibit the release of inflammatory mediators, especially from mast cells.
Resources[edit source]
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Levalbuterol for any updates.
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