Linear energy transfer
Linear energy transfer (LET) is a measure of the energy released by ionizing radiation as it travels through a medium. It is defined as the amount of energy deposited per unit length of the path of the radiation. LET is an important concept in radiation physics, radiation biology, and medical physics.
Definition[edit | edit source]
Linear energy transfer is typically expressed in units of keV/μm. It quantifies the energy transferred from ionizing particles to the material they pass through, which can be crucial for understanding the biological effects of radiation.
Types of Radiation[edit | edit source]
Different types of ionizing radiation have different LET values:
- Alpha particles: These have a high LET because they are heavy and carry a double positive charge, causing them to lose energy rapidly as they travel through matter.
- Beta particles: These have a lower LET compared to alpha particles because they are lighter and carry a single negative charge.
- Gamma rays and X-rays: These have very low LET values because they are electromagnetic waves and interact less frequently with matter.
Biological Effects[edit | edit source]
The biological impact of radiation is closely related to its LET. High-LET radiation, such as alpha particles, causes dense ionization along its path, leading to more severe biological damage. Low-LET radiation, such as gamma rays, causes sparse ionization, resulting in less immediate damage but potentially more widespread effects.
Applications[edit | edit source]
LET is a critical parameter in various fields:
- In radiation therapy, understanding LET helps in optimizing treatment plans to maximize damage to cancer cells while minimizing harm to surrounding healthy tissue.
- In radiation protection, LET is used to assess the potential health risks of different types of radiation exposure.
- In space exploration, LET is considered when evaluating the radiation hazards astronauts face from cosmic rays and solar particle events.
Measurement[edit | edit source]
LET can be measured using various techniques, including:
Related Concepts[edit | edit source]
- Relative biological effectiveness (RBE): A measure of the biological damage caused by radiation, which depends on LET.
- Dose equivalent: A quantity used in radiation protection to account for the biological effect of radiation, which incorporates LET.
See Also[edit | edit source]
- Ionizing radiation
- Radiation dosimetry
- Radiation therapy
- Radiation protection
- Relative biological effectiveness
References[edit | edit source]
External Links[edit | edit source]
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Contributors: Prab R. Tumpati, MD