Linear energy transfer

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Linear energy transfer (LET) is a measure of the energy released by ionizing radiation as it travels through a medium. It is defined as the amount of energy deposited per unit length of the path of the radiation. LET is an important concept in radiation physics, radiation biology, and medical physics.

Definition[edit | edit source]

Linear energy transfer is typically expressed in units of keV/μm. It quantifies the energy transferred from ionizing particles to the material they pass through, which can be crucial for understanding the biological effects of radiation.

Types of Radiation[edit | edit source]

Different types of ionizing radiation have different LET values:

  • Alpha particles: These have a high LET because they are heavy and carry a double positive charge, causing them to lose energy rapidly as they travel through matter.
  • Beta particles: These have a lower LET compared to alpha particles because they are lighter and carry a single negative charge.
  • Gamma rays and X-rays: These have very low LET values because they are electromagnetic waves and interact less frequently with matter.

Biological Effects[edit | edit source]

The biological impact of radiation is closely related to its LET. High-LET radiation, such as alpha particles, causes dense ionization along its path, leading to more severe biological damage. Low-LET radiation, such as gamma rays, causes sparse ionization, resulting in less immediate damage but potentially more widespread effects.

Applications[edit | edit source]

LET is a critical parameter in various fields:

  • In radiation therapy, understanding LET helps in optimizing treatment plans to maximize damage to cancer cells while minimizing harm to surrounding healthy tissue.
  • In radiation protection, LET is used to assess the potential health risks of different types of radiation exposure.
  • In space exploration, LET is considered when evaluating the radiation hazards astronauts face from cosmic rays and solar particle events.

Measurement[edit | edit source]

LET can be measured using various techniques, including:

Related Concepts[edit | edit source]

  • Relative biological effectiveness (RBE): A measure of the biological damage caused by radiation, which depends on LET.
  • Dose equivalent: A quantity used in radiation protection to account for the biological effect of radiation, which incorporates LET.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]


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Contributors: Prab R. Tumpati, MD