List of IARC Group 2A carcinogens

List of IARC Group 2A Carcinogens refers to substances, mixtures, and exposure circumstances that have been evaluated by the International Agency for Research on Cancer (IARC) and classified as Group 2A, which means they are considered to be "probably carcinogenic to humans." This classification is used to indicate that there is limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in experimental animals. Group 2A is one step below Group 1, "carcinogenic to humans," and indicates a higher level of concern than Group 2B, "possibly carcinogenic to humans."

Substances Classified as Group 2A Carcinogens

The list of Group 2A carcinogens is extensive and includes a variety of chemicals, industrial processes, and even some viruses. Examples include:

• Acrylamide - commonly found in fried or baked foods
• Diesel engine exhaust
• Indoor emissions from household combustion of coal
• Red meat (such as beef, pork, and lamb)
• Ultraviolet (UV) radiation, specifically from tanning beds
• Human papillomavirus type 68 (HPV-68)
• Hot Yerba Mate - a type of tea

This list is not exhaustive, and the IARC regularly updates its classifications based on new research.

Evaluation Process

The IARC's evaluations are conducted by international working groups of experts who review published studies and other relevant data to assess the potential of agents to cause cancer in humans. The classification into Group 2A is based on the strength of the evidence from studies in humans, studies in experimental animals, and mechanistic and other relevant data.

Implications of Classification

The classification of an agent as a Group 2A carcinogen does not mean that the agent will definitely cause cancer in every exposure scenario. Instead, it indicates that the agent has the potential to cause cancer under certain conditions of exposure. The level of risk depends on several factors, including the amount and duration of exposure.

Preventive Measures

To reduce the risk of exposure to Group 2A carcinogens, individuals and workplaces can adopt various preventive measures. These may include:

• Reducing consumption of red meat and processed meats
• Using proper ventilation when cooking or heating with coal indoors
• Avoiding the use of tanning beds
• Implementing safety measures and using protective equipment in industries that involve exposure to diesel exhaust or other hazardous substances

See Also

• International Agency for Research on Cancer
• Carcinogen
• List of IARC Group 1 carcinogens
• List of IARC Group 2B carcinogens

References

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