List of MeSH codes (D12)

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List of MeSH codes (D12) refers to a comprehensive categorization within the Medical Subject Headings (MeSH) system, specifically focusing on the section designated as D12. MeSH is a hierarchical vocabulary used for indexing, cataloging, and searching for biomedical and health-related information. It covers a wide range of topics, allowing for precise and consistent retrieval of information. The D12 category encompasses the field of Amino Acids, Peptides, and Proteins, which is fundamental to the study of biology, biochemistry, and medicine.

Overview[edit | edit source]

The D12 category of MeSH codes is subdivided into various subcategories that detail the different types of amino acids, peptides, and proteins, their functions, structures, and roles in health and disease. This categorization facilitates the organization and retrieval of vast amounts of research articles, clinical studies, and educational materials related to these biomolecules.

Subcategories[edit | edit source]

The D12 category includes several subcategories, each focusing on specific aspects of amino acids, peptides, and proteins. Some of the notable subcategories are:

  • Amino Acids: This subcategory includes codes for individual amino acids, their derivatives, and analogs. It covers essential and non-essential amino acids, their biochemical properties, and their roles in metabolic processes.
  • Peptides: This includes short chains of amino acid monomers linked by peptide bonds. Peptides are classified based on their length, function, and origin. This subcategory covers everything from dipeptides to polypeptides and their biological activities.
  • Proteins: Proteins, composed of one or more long chains of amino acid residues, are essential to the structure and function of all living cells and viruses. This subcategory includes structural proteins, enzymes, transport proteins, and antibodies, among others.
  • Enzymes: Enzymes are proteins that act as biological catalysts, speeding up chemical reactions in the body. This subcategory includes classifications based on the type of reaction catalyzed, such as hydrolases, oxidoreductases, and transferases.
  • Protein Conformation: This subcategory deals with the three-dimensional shape of proteins and how it relates to their function and stability. It includes topics such as protein folding, denaturation, and conformational changes.

Importance[edit | edit source]

Understanding the structure, function, and interactions of amino acids, peptides, and proteins is crucial for the development of new therapies, drugs, and diagnostic methods. The MeSH D12 codes provide a structured way to access and analyze the vast amount of research data in these areas, supporting advancements in biomedical research and healthcare.

Conclusion[edit | edit source]

The List of MeSH codes (D12) serves as an essential tool for researchers, clinicians, and students in the fields of biochemistry, molecular biology, and medicine. By categorizing information related to amino acids, peptides, and proteins, it facilitates efficient retrieval and analysis of relevant literature, contributing to ongoing scientific discovery and medical innovation.

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Contributors: Prab R. Tumpati, MD