List of human leukocyte antigen alleles associated with cutaneous conditions

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List of Human Leukocyte Antigen Alleles Associated with Cutaneous Conditions

Human leukocyte antigens (HLAs) are proteins located on the surface of white blood cells and other tissues in the body. They play a crucial role in the immune system by helping the body distinguish between its own cells and foreign invaders. Certain HLA alleles have been associated with various cutaneous (skin) conditions. This article provides a list of these HLA alleles and the skin conditions they are linked to.

HLA Alleles and Associated Cutaneous Conditions[edit | edit source]

  • HLA-B27
 * Psoriasis
 * Psoriatic arthritis
 * Reactive arthritis
  • HLA-B51
 * Behçet's disease
  • HLA-Cw6
 * Psoriasis
  • HLA-DR4
 * Pemphigus vulgaris
  • HLA-DRB1*0401
 * Rheumatoid arthritis (with cutaneous manifestations)
  • HLA-DRB1*1501
 * Systemic lupus erythematosus (with cutaneous manifestations)
  • HLA-DQ2 and HLA-DQ8
 * Dermatitis herpetiformis

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Contributors: Prab R. Tumpati, MD