List of side effects of estradiol

Estradiol is a form of estrogen, a hormone that plays a critical role in the regulation of the reproductive and menstrual cycle. It is also used in hormone therapy for transgender women and postmenopausal symptoms in cisgender women. While estradiol is essential for many bodily functions, its use, whether through hormone replacement therapy (HRT), contraceptive pills, or other means, can lead to various side effects. This article aims to provide a comprehensive list of the side effects associated with estradiol use.

Common Side Effects[edit | edit source]

Common side effects of estradiol may include, but are not limited to:

Serious Side Effects[edit | edit source]

While less common, there are serious side effects associated with estradiol that require immediate medical attention:

Psychological Side Effects[edit | edit source]

Estradiol can also affect mental health, with some individuals experiencing:

Depression
Anxiety
Changes in libido

Long-term Side Effects[edit | edit source]

Long-term use of estradiol may increase the risk of:

Breast cancer
Endometrial cancer (in patients with a uterus)
Ovarian cancer
Dementia in postmenopausal women over the age of 65

Interactions[edit | edit source]

Estradiol can interact with other medications, leading to increased side effects or decreased effectiveness of treatments. It is important to discuss all medications, including over-the-counter drugs and supplements, with a healthcare provider.

Precautions[edit | edit source]

Before starting estradiol, individuals should inform their healthcare provider about any pre-existing conditions such as:

Conclusion[edit | edit source]

While estradiol is an effective treatment for many conditions, it is important to be aware of the potential side effects. Monitoring and regular check-ups with a healthcare provider can help manage and mitigate these risks.

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