Lotrel

- having a substantial blood pressure lowering capability, amlodipine besylate benazepril hydrochloride contains a dihydropyridine calcium blocker (amlodipine) and an angiotensin converting enzyme (ace) inhibitor (benazepril). A long acting calcium channel antagonist, amlodipine inhibits transmembrane calcium influx into vascular smooth muscle. Blocking ace, benazepril decreases vasopressive plasma angiotensin ii. (nci04)

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