Lumiflavin

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Lumiflavin

Lumiflavin is a yellow-green fluorescent compound that is a derivative of riboflavin (vitamin B2). It is formed when riboflavin is exposed to light, leading to the cleavage of the ribityl side chain. Lumiflavin is known for its role in the study of flavin biochemistry and photochemistry.

Chemical Structure and Properties[edit | edit source]

Lumiflavin has the chemical formula C13H12N4O2 and a molecular weight of 256.26 g/mol. It is characterized by its yellow-green fluorescence under ultraviolet light. The compound is relatively stable in the dark but degrades upon exposure to light, especially in the presence of oxygen.

Formation and Degradation[edit | edit source]

Lumiflavin is formed from riboflavin through a photochemical reaction. When riboflavin is exposed to light, particularly ultraviolet light, it undergoes a photolytic cleavage of the ribityl side chain, resulting in the formation of lumiflavin. This process is significant in the study of photodegradation of vitamins and other biological molecules.

Biological Significance[edit | edit source]

While lumiflavin itself does not have a direct biological role, its formation and properties are important in understanding the behavior of riboflavin and other flavins under light exposure. This knowledge is crucial in fields such as biochemistry, nutrition, and pharmacology.

Applications[edit | edit source]

Lumiflavin is used in various scientific studies to investigate the photochemical properties of flavins. It serves as a model compound in research on the stability and degradation of riboflavin in food and pharmaceutical products. Additionally, lumiflavin's fluorescence properties make it useful in fluorescence spectroscopy and related analytical techniques.

Related Compounds[edit | edit source]

Lumiflavin is closely related to other flavin compounds, including:

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD