Lysine acetylsalicylate

Lysine acetylsalicylate is a drug that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is a salt of acetylsalicylic acid, commonly known as aspirin, and lysine, an essential amino acid.

Pharmacology

Lysine acetylsalicylate is used for its analgesic, antipyretic, and anti-inflammatory properties. It works by inhibiting the production of prostaglandins, substances in the body that cause inflammation, pain, and fever. The addition of lysine to acetylsalicylic acid enhances the solubility of the drug, allowing for faster absorption and onset of action.

Indications

Lysine acetylsalicylate is indicated for the relief of mild to moderate pain, reduction of fever, and management of inflammatory conditions. It is also used in the prevention of cardiovascular disease, including myocardial infarction and stroke, due to its antiplatelet effect.

Side Effects

Like other NSAIDs, lysine acetylsalicylate can cause gastrointestinal side effects, including nausea, vomiting, diarrhea, and gastric ulceration. Other potential side effects include allergic reactions, bleeding, and kidney damage.

Contraindications

Lysine acetylsalicylate is contraindicated in patients with known hypersensitivity to acetylsalicylic acid or other NSAIDs. It should also be avoided in patients with active peptic ulcer disease, severe renal impairment, or bleeding disorders.

Interactions

Lysine acetylsalicylate can interact with several other medications, including anticoagulants, corticosteroids, and other NSAIDs. These interactions can increase the risk of bleeding and other side effects.

See Also

• Acetylsalicylic acid
• Nonsteroidal anti-inflammatory drugs
• Lysine