MCPP

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MCPP


MCPP (Meta-Chlorophenylpiperazine) is a psychoactive drug of the piperazine chemical class. It is known to produce serotonin receptor-mediated psychoactive effects, and is commonly used in scientific research.

History[edit | edit source]

MCPP was first synthesized in the 1970s by the pharmaceutical company Upjohn. It was initially developed as a potential antidepressant medication, but its use in this capacity has been limited due to its side effects.

Pharmacology[edit | edit source]

MCPP acts primarily as a serotonin receptor agonist. It has a high affinity for the 5-HT2A and 5-HT2C receptors, and a lower affinity for the 5-HT1A receptor. This activity at the serotonin receptors is thought to be responsible for its psychoactive effects.

Effects[edit | edit source]

The effects of MCPP can vary widely depending on the dose and individual's physiology. Common effects include euphoria, anxiety, insomnia, and nausea. In rare cases, MCPP can cause serotonin syndrome, a potentially life-threatening condition.

Legal Status[edit | edit source]

The legal status of MCPP varies by country. In some countries, it is a controlled substance, while in others it is legal to possess and use.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD