Upjohn

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Upjohn's Friable Pills
Unicap Upjohn

Upjohn was a pharmaceutical company founded in 1886 in Kalamazoo, Michigan by Dr. William E. Upjohn, who developed a new method to create friable pills which were easier to digest. The company was a pioneer in the pharmaceutical industry, introducing many innovations and contributing significantly to the field of medicine.

History[edit | edit source]

The Upjohn Company began with Dr. Upjohn's invention of the "friable pill", which was an immediate success and set the stage for the company's future in developing and marketing pharmaceuticals. Over the years, Upjohn became known for its research and development in various areas of medicine, including steroid chemistry and antifungal drugs. One of its most notable products was Cortisone, a steroid that revolutionized the treatment of arthritis and other inflammatory diseases.

In the 20th century, Upjohn continued to expand, both in terms of its product line and its geographical reach. The company was responsible for the introduction of several other important drugs, including Halcion (triazolam), a benzodiazepine used to treat insomnia, and Rogaine (minoxidil), the first drug approved by the FDA to treat male pattern baldness.

Merger and Legacy[edit | edit source]

In 1995, Upjohn merged with Pharmacia AB of Sweden to form Pharmacia & Upjohn. This merger was part of a trend in the pharmaceutical industry towards consolidation, as companies sought to pool resources for drug development and expand their market presence. The combined entity later merged with Monsanto in 2000, which was then acquired by Pfizer in 2003. Despite these changes, the Upjohn name remained associated with a range of pharmaceutical products and continued to be recognized for its contributions to medicine.

Impact on the Pharmaceutical Industry[edit | edit source]

Upjohn's legacy in the pharmaceutical industry is marked by its commitment to innovation and quality in drug development. The company's research contributed to significant advancements in medical treatment and patient care. Upjohn was also known for its ethical standards in testing and marketing drugs, setting a precedent for the industry.

Products[edit | edit source]

Some of the key products developed by Upjohn include:

  • Cortisone – A groundbreaking steroid medication for inflammation.
  • Halcion – A short-acting benzodiazepine for insomnia.
  • Rogaine – The first FDA-approved treatment for hair loss.
  • Xanax (alprazolam) – A benzodiazepine for anxiety disorders, which became one of the most prescribed medications in the United States.

Conclusion[edit | edit source]

The Upjohn Company played a significant role in the development of the pharmaceutical industry, introducing innovative products and practices that have had a lasting impact on healthcare. Although the company has undergone several mergers and its name is no longer used, its legacy continues in the products and research that originated from its efforts.


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Contributors: Prab R. Tumpati, MD