MIR95
MIR95 is a microRNA that plays a significant role in various biological processes, including cell differentiation, proliferation, apoptosis, and development. It is part of the larger family of non-coding RNA molecules that regulate gene expression at the post-transcriptional level.
Function[edit | edit source]
MIR95, like other microRNAs, functions by binding to the mRNA of target genes and inhibiting their translation into proteins. This process is crucial for the regulation of gene expression, and any alterations in this mechanism can lead to various diseases, including cancer.
Role in Disease[edit | edit source]
Research has shown that MIR95 is often dysregulated in several types of cancer, including breast cancer, lung cancer, and colorectal cancer. In these cases, MIR95 acts as an oncogene, promoting tumor growth and progression. It does this by targeting and downregulating various tumor suppressor genes, leading to uncontrolled cell proliferation.
Therapeutic Potential[edit | edit source]
Due to its role in disease, MIR95 has been identified as a potential therapeutic target. Strategies aimed at inhibiting MIR95 could potentially slow down tumor growth and progression, providing a new avenue for cancer treatment.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD