MPPF

From WikiMD's Wellness Encyclopedia

MPPF (4,4'-Methylenediphenyl diisocyanate) is a potent and selective antagonist of the serotonin 5-HT1A receptor. It is used in scientific research to study the role of the 5-HT1A receptor in the action of drugs and in various biological processes.

Chemistry[edit | edit source]

MPPF is a chemical compound with the molecular formula C17H15NO2. It is a derivative of phenylisocyanate, with two phenyl groups attached to a central carbon atom. The compound is a solid at room temperature and is soluble in organic solvents.

Pharmacology[edit | edit source]

MPPF acts as an antagonist at the 5-HT1A receptor, meaning it blocks the action of serotonin at this receptor. This makes it a useful tool in research to study the role of the 5-HT1A receptor in various biological processes, including mood regulation, anxiety, and the action of certain drugs.

Uses in Research[edit | edit source]

MPPF has been used in a variety of research studies to investigate the role of the 5-HT1A receptor. For example, it has been used to study the effects of drugs that act on the 5-HT1A receptor, such as antidepressants and anxiolytics. It has also been used to investigate the role of the 5-HT1A receptor in mood regulation and anxiety.

Safety[edit | edit source]

As with all chemicals, MPPF should be handled with care. It is not intended for human consumption and should be used only in a laboratory setting by trained professionals.

See Also[edit | edit source]

MPPF Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD