Mammillothalamic tract
Mammillothalamic tract is a part of the brain that plays a significant role in memory formation. It is a component of the Papez circuit, which is involved in the control and expression of emotions. The mammillothalamic tract connects the mammillary bodies and the anterior thalamic nuclei.
Etymology[edit | edit source]
The term "mammillothalamic tract" is derived from the Latin words "mammillo" meaning "small breast" and "thalamic" meaning "inner chamber". This is in reference to the anatomical locations of the mammillary bodies and the thalamus in the brain.
Anatomy[edit | edit source]
The mammillothalamic tract originates from the mammillary bodies, which are a pair of small round bodies located on the undersurface of the brain. It then ascends to the anterior thalamic nuclei, which are a group of nuclei located in the thalamus.
Function[edit | edit source]
The mammillothalamic tract is involved in the transmission of information related to memory from the mammillary bodies to the anterior thalamic nuclei. This pathway is a crucial component of the Papez circuit, which is involved in the control and expression of emotions.
Clinical significance[edit | edit source]
Damage to the mammillothalamic tract can result in memory disorders such as Korsakoff's syndrome. This is a chronic memory disorder caused by severe deficiency of thiamine (vitamin B-1). The most common cause is alcohol misuse, but certain other conditions can also cause the syndrome.
See also[edit | edit source]
References[edit | edit source]
Mammillothalamic tract Resources | |
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Contributors: Prab R. Tumpati, MD