Medroxyprogesterone

Medroxyprogesterone is a type of progestin, a class of hormone that mimics the effects of naturally occurring progesterone. It is used in a variety of medical applications, including as a component of hormone replacement therapy, in the treatment of abnormal uterine bleeding, and as a method of birth control.

Medical Uses

Medroxyprogesterone is used in the treatment of a variety of medical conditions. It is often prescribed as part of hormone replacement therapy for menopausal women, to help alleviate symptoms such as hot flashes and vaginal dryness. It is also used to treat abnormal uterine bleeding, by helping to regulate the menstrual cycle.

In addition, medroxyprogesterone is used as a method of birth control. It is the active ingredient in the Depo-Provera injection, which provides protection against pregnancy for three months at a time.

Side Effects

Like all medications, medroxyprogesterone can cause side effects. These may include nausea, bloating, breast tenderness, and changes in menstrual bleeding patterns. In rare cases, it can cause more serious side effects such as blood clots, stroke, or heart attack.

Pharmacology

Medroxyprogesterone works by mimicking the effects of naturally occurring progesterone. It binds to progesterone receptors in the body, which helps to regulate the menstrual cycle and prevent ovulation.

History

Medroxyprogesterone was first synthesized in the 1950s, and has been used in medical practice since the 1960s. It is now one of the most commonly prescribed progestins in the world.

See Also

• Hormone replacement therapy
• Progestin
• Depo-Provera