Melatonin receptor 1B
Melatonin receptor 1B (also known as MTNR1B) is a protein that in humans is encoded by the MTNR1B gene. It is one of the two high-affinity forms of serotonin receptors found in the pineal gland and the retina.
Function[edit]
The MTNR1B receptor is a member of the G protein-coupled receptor family and is an integral part of the melatonin signal transduction pathway. Melatonin is a hormone produced in the pineal gland and is involved in the regulation of circadian rhythms. The MTNR1B receptor is thought to influence a variety of biological functions, including sleep, mood, and immune system function.
Clinical significance[edit]
Mutations in the MTNR1B gene have been associated with an increased risk of type 2 diabetes. This is thought to be due to the role of melatonin in regulating insulin secretion. Additionally, variations in the MTNR1B gene have been linked to polycystic ovary syndrome (PCOS), suggesting a role for this receptor in reproductive function.
See also[edit]
References[edit]
External links[edit]
- MTNR1B at the National Center for Biotechnology Information
 | This Human chromosome 11 gene article is a stub. You can help WikiMD by expanding the page. |
 | This medical article is a stub. You can help WikiMD by expanding the page. |
Sponsored Health Resource
W8MD Weight Loss, Sleep & MedSpa
Looking for physician-supervised weight loss, semaglutide, tirzepatide, or GLP-1 receptor agonist options? W8MD helps eligible patients in New York City, Brooklyn, New Jersey, Connecticut, Pennsylvania, Delaware, and greater Philadelphia with medical weight loss, sleep medicine, and long-term maintenance support.
GLP-1 specials: Affordable GLP-1 injections NYC and Philadelphia starting from $29.99/week and up for semaglutide with insurance accepted for qualifying visits, and $45/week and up for tirzepatide with insurance accepted for qualifying visits. Self-pay options start from $59.99/week and up for semaglutide and $69.99/week and up for tirzepatide.
- Medical weight loss NYC
- Affordable GLP-1 injections NYC
- Budget GLP-1 weight loss shots Philadelphia
- New Jersey medical weight loss
- NYC medical weight loss blog
- Philadelphia weight loss blog
- Sleep medicine and sleep apnea services
- W8MD MedSpa and wellness
Book a W8MD appointment · View GLP-1 specials
Paid promotional message. Eligibility, pricing, insurance coverage, medication availability, and results vary. Medical evaluation required.
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
