Metallosis

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Metallosis is a type of medical condition that occurs when metallic debris builds up in the soft tissues of the body. This condition is often associated with certain types of joint replacement surgeries, particularly hip replacement and knee replacement surgeries that use metal-on-metal (MoM) devices.

Causes[edit | edit source]

Metallosis is typically caused by wear and tear on metal-on-metal joint replacements. Over time, the friction between the metal components can cause tiny metal particles to shed into the surrounding tissue and bloodstream. This can lead to a reaction that causes damage to the soft tissues around the joint, leading to pain, device failure, and other complications.

Symptoms[edit | edit source]

The symptoms of metallosis can vary depending on the severity of the condition and the individual patient's response to metal debris. Common symptoms include:

  • Pain around the joint
  • Swelling and inflammation
  • Difficulty walking or moving the joint
  • A feeling of instability in the joint
  • Unexplained hip or knee problems after joint replacement surgery

In severe cases, metallosis can lead to systemic symptoms such as cardiomyopathy, neurological changes, psychological changes, renal function impairment, and thyroid dysfunction.

Diagnosis[edit | edit source]

Diagnosis of metallosis typically involves a combination of patient history, physical examination, and diagnostic tests. Blood tests may be used to measure the level of metal ions in the blood, and imaging tests such as MRI or ultrasound may be used to assess the condition of the joint and surrounding tissues.

Treatment[edit | edit source]

Treatment for metallosis typically involves removing the metal-on-metal joint replacement and replacing it with a device made from other materials, such as ceramic or polyethylene. In some cases, medication may be used to manage symptoms and reduce inflammation.

Prevention[edit | edit source]

Prevention of metallosis primarily involves the use of joint replacement devices made from materials other than metal. Regular follow-up appointments after joint replacement surgery can also help to detect any potential problems early.

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Contributors: Prab R. Tumpati, MD