Metergoline
Metergoline is a pharmacological agent that is classified as an ergot alkaloid. It is primarily used in the treatment of migraines and cluster headaches. Metergoline works by inhibiting the action of serotonin in the brain, which can help to alleviate the symptoms of these conditions.
Pharmacology[edit | edit source]
Metergoline is an ergot alkaloid, a class of compounds derived from the fungus Claviceps purpurea. Ergot alkaloids have a variety of pharmacological effects, but metergoline is primarily used for its anti-serotonergic properties. It works by binding to and inhibiting the action of serotonin receptors in the brain.
Medical Uses[edit | edit source]
The primary use of metergoline is in the treatment of migraines and cluster headaches. These conditions are thought to be caused, at least in part, by overactivity of the serotonin system in the brain. By inhibiting the action of serotonin, metergoline can help to alleviate the symptoms of these conditions.
Side Effects[edit | edit source]
Like all medications, metergoline can cause side effects. The most common side effects include nausea, vomiting, and dizziness. In rare cases, metergoline can cause more serious side effects, such as hallucinations or psychosis. If you experience any unusual or severe side effects while taking metergoline, you should contact your doctor immediately.
Contraindications[edit | edit source]
Metergoline is contraindicated in individuals with a history of psychosis or other serious mental health conditions. It is also contraindicated in individuals with certain cardiovascular conditions, as it can increase the risk of heart attack or stroke.
See Also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
