Metergoline

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Metergoline is a pharmacological agent that is classified as an ergot alkaloid. It is primarily used in the treatment of migraines and cluster headaches. Metergoline works by inhibiting the action of serotonin in the brain, which can help to alleviate the symptoms of these conditions.

Pharmacology[edit | edit source]

Metergoline is an ergot alkaloid, a class of compounds derived from the fungus Claviceps purpurea. Ergot alkaloids have a variety of pharmacological effects, but metergoline is primarily used for its anti-serotonergic properties. It works by binding to and inhibiting the action of serotonin receptors in the brain.

Medical Uses[edit | edit source]

The primary use of metergoline is in the treatment of migraines and cluster headaches. These conditions are thought to be caused, at least in part, by overactivity of the serotonin system in the brain. By inhibiting the action of serotonin, metergoline can help to alleviate the symptoms of these conditions.

Side Effects[edit | edit source]

Like all medications, metergoline can cause side effects. The most common side effects include nausea, vomiting, and dizziness. In rare cases, metergoline can cause more serious side effects, such as hallucinations or psychosis. If you experience any unusual or severe side effects while taking metergoline, you should contact your doctor immediately.

Contraindications[edit | edit source]

Metergoline is contraindicated in individuals with a history of psychosis or other serious mental health conditions. It is also contraindicated in individuals with certain cardiovascular conditions, as it can increase the risk of heart attack or stroke.

See Also[edit | edit source]


Metergoline Resources

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