Methylenedioxyethamphetamine

Methylenedioxyethamphetamine

Methylenedioxyethamphetamine, commonly known as MDMA or "Ecstasy", is a psychoactive drug primarily used for recreational purposes. The drug is known for its euphoric and empathogenic effects. It is classified as a serotonin-norepinephrine-dopamine releasing agent (SNDRA).

History

MDMA was first synthesized in 1912 by the pharmaceutical company Merck KGaA. It was initially patented for use as a diet aid, but it was never marketed for this purpose. The drug gained popularity in the 1980s as a party drug and is still widely used today.

Pharmacology

MDMA acts primarily by increasing the activity of the neurotransmitters serotonin, dopamine, and norepinephrine in certain parts of the brain. It has a high affinity for the serotonin transporter, which leads to increased extracellular concentrations of serotonin.

Effects

The effects of MDMA include feelings of euphoria, increased sociability, and heightened sensory perception. However, it can also cause a number of adverse effects, including nausea, hyperthermia, and dehydration. Long-term use can lead to neurotoxicity and cognitive deficits.

Legal status

MDMA is classified as a Schedule I controlled substance in the United States, meaning it has a high potential for abuse and no accepted medical use. However, it is currently being studied for potential therapeutic uses in the treatment of post-traumatic stress disorder (PTSD) and other conditions.

See also

• Amphetamine
• Methamphetamine
• Psychedelic drug
• Recreational drug use

References

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