Methylenedioxyhydroxymethamphetamine

Methylenedioxyhydroxymethamphetamine (MDHMA) is a psychoactive drug that is primarily used for recreational purposes. It is a member of the substituted amphetamine class of drugs, which also includes methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA).

History

MDHMA was first synthesized in the 1960s by Alexander Shulgin, a renowned chemist known for his work on psychoactive substances. However, it did not gain widespread popularity until the 1980s and 1990s, when it began to be used in the rave and clubbing scenes.

Pharmacology

MDHMA acts primarily as a serotonin-norepinephrine-dopamine releasing agent (SNDRA). This means that it increases the levels of these neurotransmitters in the brain, leading to feelings of euphoria, increased energy, and heightened sensory perception.

Effects

The effects of MDHMA can vary widely depending on the dose, the individual's physiology, and the environment in which it is taken. Common effects include feelings of euphoria, increased energy, and heightened sensory perception. However, it can also cause negative effects such as anxiety, paranoia, and in rare cases, severe health complications such as hyperthermia and serotonin syndrome.

Legal status

MDHMA is currently classified as a Schedule I controlled substance in the United States, meaning it is illegal to manufacture, distribute, or possess without a license. It is also illegal in many other countries, including the United Kingdom and Australia.

See also

• Phenethylamine
• Psychedelic drug
• Recreational drug use