Methylone

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Methylone is a psychoactive drug that is used primarily for recreational drug use. It is a substituted cathinone and is chemically similar to the cathinone compounds found in the khat plant of eastern Africa. Methylone was first synthesized by the chemists Alexander Shulgin and Ann Shulgin for potential use in psychotherapy.

History[edit | edit source]

Methylone was first synthesized in 1996 by Alexander Shulgin and Ann Shulgin. It was intended to be used as a potential therapeutic tool in psychotherapy, but it has since been primarily used recreationally.

Pharmacology[edit | edit source]

Methylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. This is done by inhibiting the reuptake of these neurotransmitters by the neurons. Additionally, it releases these neurotransmitters from the neurons into the synaptic cleft.

Effects[edit | edit source]

The effects of Methylone are similar to those of MDMA, but it does not produce the same level of sensory enhancement or empathogenesis. The effects include feelings of euphoria, increased sociability, mental and physical stimulation, and a heightened sense of empathy and love.

Legal Status[edit | edit source]

The legal status of Methylone varies by country. In the United States, it is a Schedule I controlled substance. In the United Kingdom, it is a Class B drug. In Canada, it is a Schedule III drug.

See Also[edit | edit source]


Methylone Resources

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Contributors: Prab R. Tumpati, MD