Metopimazine

From WikiMD's Food, Medicine & Wellness Encyclopedia

Metopimazine is a phenothiazine derivative that is used as an antiemetic. It is commonly used in Europe, but is not available in the United States.

Etymology[edit | edit source]

The term "Metopimazine" is derived from the Greek words "metopon" (forehead) and "imazo" (to imagine), referring to the drug's effect on the brain's ability to perceive nausea and vomiting.

Pharmacology[edit | edit source]

Metopimazine acts as a highly selective D2 receptor antagonist. It is used to prevent nausea and vomiting that can occur postoperatively or as a result of receiving chemotherapy or radiotherapy.

Side Effects[edit | edit source]

Like other phenothiazines, metopimazine can cause a variety of side effects. These can include drowsiness, dizziness, and orthostatic hypotension. In rare cases, it can cause extrapyramidal symptoms such as tardive dyskinesia.

Related Terms[edit | edit source]

See Also[edit | edit source]

Metopimazine Resources
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Contributors: Prab R. Tumpati, MD