Midrin
- a combination preparation containing isometheptane, dichloralphenazone and acetaminophen with analgesic activity. Isometheptene is an indirect acting sympathomimetic agent with vasoconstricting activity, thereby reducing the pulsation in cerebral arteries by constricting dilated cerebral blood vessels. Dichloralphenazone, a complex of chloral hydrate, which possesses hypnotic and sedative activity, and antipyrine, a pyrazolone analgesic and an antipyretic. Acetaminophen inhibits prostaglandin synthesis, thereby exerting analgesic activity. This preparation is used for the relief of migraine and tension headaches.
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Midrin for any updates.
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