Minamestane

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Minamestane is a steroidal aromatase inhibitor that is related to exemestane. It was under development for the treatment of breast cancer and infertility but was never marketed.

Chemistry[edit | edit source]

Minamestane, also known as 6-methylenandrosta-1,4-diene-3,17-dione, is a synthetic, steroidal aromatase inhibitor. It is structurally related to exemestane, another steroidal aromatase inhibitor.

Pharmacology[edit | edit source]

Minamestane acts as an inhibitor of aromatase, an enzyme that is involved in the production of estrogen in the body. By inhibiting this enzyme, minamestane can reduce the levels of estrogen in the body, which can be beneficial in conditions that are influenced by this hormone, such as breast cancer and infertility.

Clinical development[edit | edit source]

Minamestane was under development for the treatment of breast cancer and infertility, but it was never marketed. The reasons for this are not clear, but it may be due to the development of other, more effective aromatase inhibitors.

See also[edit | edit source]

Minamestane Resources
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Contributors: Prab R. Tumpati, MD