Msh homeobox 2
Msh homeobox 2 (also known as MSX2) is a protein that in humans is encoded by the MSX2 gene. This protein is part of the homeobox family, a group of genes that play crucial roles in cell differentiation and morphogenesis during embryonic development.
Function[edit | edit source]
The MSX2 protein is a transcription factor, which means it binds to specific sequences of DNA and controls the transcription of genetic information from DNA to mRNA. MSX2 is particularly important in the development of the nervous system, skeletal system, and hair follicles.
Clinical significance[edit | edit source]
Mutations in the MSX2 gene have been associated with several medical conditions. For example, a specific mutation can cause Boston-type craniosynostosis, a condition characterized by the premature fusion of the skull bones. Other mutations can lead to hypoplastic nails and dysplastic teeth.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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