Multifactorial
Multifactorial refers to a trait or disorder determined by multiple genes on different chromosomes, combined with environmental factors. Multifactorial disorders include heart disease, high blood pressure, Alzheimer's disease, arthritis, diabetes, cancer, and obesity.
Genetics[edit | edit source]
Multifactorial inheritance, also known as polygenic inheritance, is a type of non-Mendelian inheritance. Unlike Mendelian inheritance, where traits are controlled by a single gene, multifactorial traits are controlled by multiple genes and environmental factors.
Environmental Factors[edit | edit source]
Environmental factors play a significant role in the expression of multifactorial traits. These factors can include diet, exercise, exposure to toxins, and stress. The interaction between genetic factors and environmental factors can lead to a wide range of phenotypic outcomes.
Disorders[edit | edit source]
Multifactorial disorders are common and include a wide range of conditions. These disorders often have a significant impact on an individual's health and quality of life. Some examples of multifactorial disorders include:
Prevention and Treatment[edit | edit source]
Prevention and treatment of multifactorial disorders often involve lifestyle changes and medication. Genetic counseling may also be beneficial for individuals with a family history of a multifactorial disorder.
See Also[edit | edit source]
- Genetics
- Environmental Factors
- Heart disease
- High blood pressure
- Alzheimer's disease
- Arthritis
- Diabetes
- Cancer
- Obesity
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Contributors: Prab R. Tumpati, MD
