Muscarinic toxin 7
Muscarinic toxin 7 (MT7) is a protein that is part of the muscarinic toxin family. These toxins are derived from the venom of the green mamba snake and have a high affinity for muscarinic acetylcholine receptors.
Structure[edit | edit source]
Muscarinic toxin 7 is a small protein composed of 65 amino acids. It has a three-finger fold structure, which is common among snake venom toxins. This structure allows the toxin to interact with its target receptors.
Function[edit | edit source]
Muscarinic toxin 7 specifically targets the M1 and M4 subtypes of muscarinic acetylcholine receptors. These receptors are found in the central nervous system and play a crucial role in cognitive functions such as learning and memory. By binding to these receptors, MT7 can affect their function and potentially lead to neurological disorders.
Clinical significance[edit | edit source]
Due to its ability to bind to muscarinic acetylcholine receptors, muscarinic toxin 7 has been studied for its potential use in the treatment of various neurological disorders, including Alzheimer's disease and Parkinson's disease. However, more research is needed to fully understand the potential therapeutic applications of this toxin.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD