N-Methyl-N-ethyltryptamine

N-Methyl-N-ethyltryptamine (NET) is a psychedelic and entheogenic drug that is structurally related to other tryptamine derivatives. It is known for its hallucinogenic effects, which are similar to those of other psychedelic substances such as DMT and psilocybin.

Chemistry

N-Methyl-N-ethyltryptamine is a member of the tryptamine class of compounds, which are structurally similar to the amino acid tryptophan. It is a derivative of tryptamine with two additional alkyl groups attached to the nitrogen atom, specifically a methyl and an ethyl group. This modification increases the lipophilicity of the molecule, which can enhance its ability to cross the blood-brain barrier and exert its effects in the brain.

Pharmacology

The exact mechanism of action of N-Methyl-N-ethyltryptamine is not fully understood. However, it is believed to act primarily as a serotonin receptor agonist, similar to other psychedelic tryptamines. This means it binds to and activates these receptors, leading to an increase in serotonin activity in the brain. This increased activity is thought to be responsible for the drug's hallucinogenic effects.

Effects

The effects of N-Methyl-N-ethyltryptamine can vary widely depending on the dose, the individual's physiology, and the context in which it is used. Common effects reported by users include visual and auditory hallucinations, altered perception of time and space, enhanced introspection, and feelings of euphoria. However, negative effects such as anxiety, paranoia, and physical discomfort can also occur.

Legal Status

The legal status of N-Methyl-N-ethyltryptamine varies by country. In some jurisdictions, it is classified as a controlled substance and its possession, sale, or use is prohibited. In others, it may be legal for research or therapeutic use under certain conditions.

See Also

• Tryptamine
• Psychedelic drug
• Serotonin receptor