NAP1L3

NAP1L3 or Nucleosome Assembly Protein 1 Like 3 is a protein that in humans is encoded by the NAP1L3 gene. It is a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation.

Function

NAP1L3 is involved in the process of nucleosome assembly, which is a fundamental process of chromatin formation. Chromatin is a complex of DNA and protein found in eukaryotic cells. Its primary function is to compress the DNA into a compact, dense shape that allows for efficient packing within the nucleus. NAP1L3, as a nucleosome assembly protein, contributes to this process by facilitating the assembly of histone proteins with DNA.

Clinical Significance

While the exact clinical significance of NAP1L3 is not fully understood, alterations in the expression of this gene have been associated with several types of cancer, including breast cancer and colorectal cancer. Further research is needed to fully understand the role of NAP1L3 in these diseases.

See Also

• Nucleosome
• Chromatin
• Cancer

References

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