Naratriptan hydrochloride

Naratriptan Hydrochloride is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.

Pharmacology

Naratriptan Hydrochloride works by stimulating serotonin (a neurotransmitter) receptors in the brain which causes the muscles surrounding the blood vessels in the brain to contract and narrow the blood vessels. At the same time, it also reduces inflammatory substances in the body that can trigger head pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Medical Uses

Naratriptan Hydrochloride is primarily used to treat the symptoms of migraines with or without aura in adults. It is not used to prevent migraines, nor to treat cluster headaches or any other type of headache that is different from a migraine.

Side Effects

Common side effects of Naratriptan Hydrochloride include tingling or numbness in the fingers and toes, dizziness, warm/hot sensation, and chest/jaw/neck tightness. Serious side effects are rare, but may include blue fingers/toes/nails, cold hands/feet, hearing changes, and mood changes.

Contraindications

Naratriptan Hydrochloride should not be used by people with certain medical conditions, such as heart disease, stroke, liver disease, and high blood pressure. It should also not be used by pregnant women or those planning to become pregnant, unless clearly needed.

Interactions

Naratriptan Hydrochloride may interact with other drugs, including other migraine headache medications, antidepressants, and herbal products. It is important to keep a list of all the products you use and share it with your doctor and pharmacist.

See Also

• Triptan
• Migraine
• Serotonin