Nardil

From WikiMD's Wellness Encyclopedia

Nardil (also known as phenelzine) is a monoamine oxidase inhibitor (MAOI) that is used as an antidepressant and anxiolytic in the treatment of mood disorders and anxiety disorders, and also in the management of social anxiety disorder (SAD).

Medical uses[edit | edit source]

Nardil is primarily used to treat depression and anxiety disorders. It is particularly effective in treating atypical depression, and has also shown efficacy in the treatment of social anxiety disorder.

Side effects[edit | edit source]

Common side effects of Nardil include dizziness, drowsiness, insomnia, and weight gain. More serious side effects can include hypertension, liver damage, and serotonin syndrome.

Interactions[edit | edit source]

Nardil can interact with a number of other medications, including selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and certain dietary supplements. It is also advised to avoid certain foods while taking Nardil due to the risk of hypertensive crisis.

Pharmacology[edit | edit source]

Nardil works by inhibiting the action of monoamine oxidase, an enzyme that breaks down neurotransmitters in the brain. This results in increased levels of these neurotransmitters, which can help to alleviate symptoms of depression and anxiety.

History[edit | edit source]

Nardil was first introduced in the 1950s as a treatment for depression. It was one of the first MAOIs to be developed, and remains in use today despite the development of newer antidepressant medications.

See also[edit | edit source]

Nardil Resources
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Contributors: Prab R. Tumpati, MD