Nerve, nerve root and plexus disorders

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Nerve, Nerve Root, and Plexus Disorders encompass a range of medical conditions affecting the nervous system, specifically the nerves, nerve roots, and plexuses that coordinate and control the body's activities. These disorders can result from various causes, including injury, inflammation, compression, autoimmune diseases, and genetic disorders, leading to a wide array of symptoms depending on the nerves affected.

Causes and Risk Factors[edit | edit source]

The causes of nerve, nerve root, and plexus disorders vary widely. Physical injury from accidents, sports, or surgical procedures can lead to nerve damage. Diseases such as diabetes mellitus can cause neuropathy, affecting peripheral nerves. Inflammatory conditions, such as lupus or rheumatoid arthritis, can affect nerve function, as can infections like shingles (herpes zoster virus) which can lead to postherpetic neuralgia. Compression of nerves, as seen in carpal tunnel syndrome or cubital tunnel syndrome, is another common cause. Genetic predispositions can also play a role in conditions like Charcot-Marie-Tooth disease.

Symptoms[edit | edit source]

Symptoms of nerve, nerve root, and plexus disorders vary but often include pain, numbness, tingling, weakness, and muscle atrophy. The specific symptoms experienced by a patient depend on which nerve or group of nerves is affected. For example, disorders affecting the sciatic nerve can lead to pain and numbness in the legs, while issues with the brachial plexus can cause symptoms in the arms and hands.

Diagnosis[edit | edit source]

Diagnosis of these disorders typically involves a comprehensive medical history and physical examination, followed by diagnostic tests. These may include electromyography (EMG) and nerve conduction studies (NCS) to assess the electrical activity of muscles and the speed of nerve signal transmission, respectively. Magnetic resonance imaging (MRI) and computed tomography (CT) scans can help visualize the structure of nerves and surrounding tissues to identify any abnormalities.

Treatment[edit | edit source]

Treatment for nerve, nerve root, and plexus disorders varies based on the underlying cause and the severity of symptoms. Options may include medication for pain and inflammation, physical therapy to strengthen muscles and improve mobility, and in some cases, surgery to relieve nerve compression or repair nerve damage. For autoimmune-related conditions, treatments may also involve immunosuppressive medications.

Prevention[edit | edit source]

While not all nerve, nerve root, and plexus disorders can be prevented, maintaining a healthy lifestyle can reduce the risk of developing conditions that could lead to nerve damage. This includes managing chronic diseases like diabetes, avoiding repetitive stress injuries, and protecting against physical trauma.


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Contributors: Prab R. Tumpati, MD