Neuroregeneration

Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. It involves many different processes including the generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially the extent and speed.

Mechanisms of Neuroregeneration[edit | edit source]

Neuroregeneration can occur in the Peripheral Nervous System (PNS) and, to some extent, in the Central Nervous System (CNS). The process of neuroregeneration in PNS is significantly better than in CNS due to some reasons.

Peripheral Nervous System[edit | edit source]

In the PNS, after an injury, the proximal stump of the nerve begins to sprout axons, and the distal stump prepares for the incoming axons by expressing adhesion molecules and trophic factors.

Central Nervous System[edit | edit source]

In the CNS, the glial cells create a glial scar, inhibiting axon regeneration. The glial scar contains chondroitin sulfate proteoglycans, which inhibit axon regrowth.

Factors Affecting Neuroregeneration[edit | edit source]

Several factors can affect neuroregeneration, including age, the severity of the injury, and the location of the injury.

Neuroregeneration Research[edit | edit source]

Research in neuroregeneration involves the study of the regrowth or repair of nervous tissues, cells or cell products. This includes the generation of new neurons, glia, axons, myelin, or synapses.

References[edit | edit source]

Neuroregeneration Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.