Nevocellular nevus

A nevocellular nevus, also known as a melanocytic nevus or commonly as a mole, is a type of benign skin lesion that arises from melanocytes, the cells responsible for producing melanin, the pigment that gives skin its color. These lesions are typically pigmented and can appear anywhere on the body.

Characteristics

Nevocellular nevi are usually well-defined, round or oval, and can be flat or raised. They vary in color from light brown to black and can be present at birth (congenital) or develop later in life (acquired). Most nevi are harmless, but some can develop into melanoma, a type of skin cancer.

Causes

The development of nevocellular nevi is influenced by a combination of genetic factors and ultraviolet (UV) radiation exposure. Individuals with a family history of nevi or those with fair skin are at higher risk.

Diagnosis

Diagnosis is primarily based on clinical examination. Dermatoscopy can be used to examine the lesion more closely. In some cases, a biopsy may be performed to rule out malignancy.

Treatment

Most nevocellular nevi do not require treatment unless they show signs of change, such as asymmetry, border irregularity, color variation, diameter greater than 6mm, or evolving shape and size (ABCDE criteria). If necessary, they can be surgically removed.

Prognosis

The prognosis for individuals with nevocellular nevi is excellent, as these lesions are generally benign. However, regular monitoring is recommended to detect any changes that might indicate malignant transformation.

Related Pages

• Melanoma
• Dermatoscopy
• Biopsy
• Skin cancer
• Seborrheic keratosis
• Lentigo