Nifurtoinol

Nifurtoinol is a pharmaceutical drug used primarily in the treatment of bacterial infections. It belongs to the class of antibiotics known as nitrofurans, which are synthetic antimicrobial agents with a broad spectrum of activity.

Pharmacology

Nifurtoinol works by inhibiting the synthesis of bacterial DNA, RNA, and proteins, thereby stopping the growth of bacteria. It is bacteriostatic at low concentrations and bactericidal at high concentrations. The drug is effective against both Gram-positive and Gram-negative bacteria.

Medical Uses

Nifurtoinol is used to treat a variety of bacterial infections, including urinary tract infections, skin infections, and respiratory tract infections. It is also used in the treatment of gastrointestinal infections caused by Helicobacter pylori.

Side Effects

Like all medications, Nifurtoinol can cause side effects. Common side effects include nausea, vomiting, and diarrhea. Less common but more serious side effects can include allergic reactions, liver damage, and neuropathy.

Precautions

Patients with a history of allergy to nitrofurans should not take Nifurtoinol. It should also be used with caution in patients with kidney disease or liver disease, as these conditions can affect the drug's metabolism and increase the risk of side effects.

See Also

• Nitrofurans
• Antibiotics
• Pharmacology
• Bacterial Infections