Nigra

From WikiMD's Wellness Encyclopedia

Nigra is a term with various applications in different fields. It is most commonly used in the context of the Substantia nigra, a part of the brain, and the Via Nigra, an ancient Roman road.

Substantia Nigra[edit | edit source]

The Substantia nigra is a region in the midbrain that plays an important role in reward, addiction, and movement. Named for its dark color, it is heavily pigmented with melanin, the same substance that gives color to the skin, hair, and eyes. The Substantia nigra is divided into two parts: the pars compacta and the pars reticulata, each with distinct functions and cellular compositions.

The Substantia nigra is particularly noted for its role in Parkinson's disease, a neurodegenerative disorder characterized by the death of dopamine-producing cells in this region. This results in a variety of motor symptoms, including tremors, rigidity, and bradykinesia (slowness of movement).

Via Nigra[edit | edit source]

The Via Nigra was a road in the ancient city of Rome. It was one of the main thoroughfares in the Roman Forum, the central area around which the rest of the city was built. The Via Nigra, or "Black Street," was so named because of the dark color of the stones used in its construction.

The Via Nigra was a significant part of Roman life, serving as a main artery for commerce, politics, and social activity. Many important buildings and monuments were located along its path, including the Basilica Aemilia, one of the oldest basilicas in Rome, and the Curia Julia, the meeting place of the Roman Senate.

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Contributors: Prab R. Tumpati, MD