Nomegestrol

Nomegestrol (also known as Nomegestrol Acetate) is a progestin medication which is used in birth control pills and in the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. Nomegestrol is taken by mouth.

Pharmacology

Nomegestrol is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has strong progestogenic effects and weak anti-androgenic activity, and no other important hormonal activity.

Medical uses

Nomegestrol is used in hormone therapy for menopausal symptoms and in hormonal contraception. It is used in combination with estradiol in the contraceptive pill brand known as Zoely.

Side effects

Side effects of Nomegestrol are similar to those of other progestins. In general, progestins can cause mood changes, bloating, headache, and changes in menstrual bleeding patterns.

History

Nomegestrol was patented in 1975 and came into medical use in 1986. It is marketed widely throughout the world.

See also

• List of progestogens
• List of progestogen esters

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