Norharman

From WikiMD's Food, Medicine & Wellness Encyclopedia

Norharman is a beta-carboline alkaloid that is found in several plants and animals, as well as in many foods and drinks. It is also produced in the human body and has been detected in human tissues and body fluids. Norharman has been studied for its potential biological effects, including its possible role in Parkinson's disease, cancer, and other conditions.

Chemistry[edit | edit source]

Norharman is a member of the beta-carboline class of alkaloids, which are characterized by a three-ring structure. It is chemically related to harmine, harmaline, and other beta-carbolines. Norharman is a heterocyclic compound, meaning it contains atoms of at least two different elements in its ring structure. It is a relatively small molecule, with a molecular weight of about 182.22 g/mol.

Sources[edit | edit source]

Norharman is found in a variety of plants, including Passiflora incarnata (passionflower), Peganum harmala (Syrian rue), and Banisteriopsis caapi (ayahuasca). It is also found in several types of food and drink, including coffee, tobacco, and alcoholic beverages. In addition, norharman is produced in the human body, possibly as a result of the breakdown of tryptophan, an essential amino acid.

Biological Effects[edit | edit source]

The biological effects of norharman are not fully understood, but it has been studied for its potential role in several diseases and conditions. Some research suggests that norharman may have neuroprotective effects, and it has been investigated for its potential role in Parkinson's disease. Other studies have looked at the possible role of norharman in cancer, as it may interact with DNA and affect cell growth.

Health Risks[edit | edit source]

While norharman is naturally present in many foods and drinks, and is produced in the human body, it is not without potential health risks. Some studies have suggested that norharman may be carcinogenic, or cancer-causing, particularly when consumed in large amounts. However, more research is needed to fully understand the health risks associated with norharman.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD