Nuchal translucency measurement
Nuchal translucency measurement | |
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Purpose | Screening for chromosomal abnormalities |
Test of | Fetus |
Based on | Ultrasound |
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Nuchal Translucency Measurement is a prenatal screening test used to assess the risk of certain chromosomal abnormalities in a developing fetus. This test is typically performed during the first trimester of pregnancy, between 11 and 14 weeks of gestation.
Procedure[edit | edit source]
The nuchal translucency measurement is conducted using a specialized ultrasound technique. During the procedure, a trained sonographer measures the thickness of the nuchal translucency, which is the fluid-filled space at the back of the fetal neck. Increased thickness can be an indicator of potential chromosomal abnormalities such as Down syndrome (Trisomy 21), Trisomy 18, and Trisomy 13.
Indications[edit | edit source]
Nuchal translucency measurement is recommended for all pregnant women as part of routine prenatal screening. It is particularly advised for women who:
- Are 35 years of age or older
- Have a family history of chromosomal abnormalities
- Have had a previous pregnancy with a chromosomal abnormality
Interpretation of Results[edit | edit source]
The results of the nuchal translucency measurement are combined with other factors, such as maternal age and blood test results, to calculate the risk of chromosomal abnormalities. A higher than normal measurement may indicate an increased risk, prompting further diagnostic testing such as chorionic villus sampling (CVS) or amniocentesis.
Limitations[edit | edit source]
While nuchal translucency measurement is a useful screening tool, it is not diagnostic. It cannot definitively determine the presence of a chromosomal abnormality. False positives and false negatives can occur, and further testing is required to confirm any findings.
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Contributors: Prab R. Tumpati, MD