Nuclear moulding
Nuclear moulding is a term used in pathology to describe the alteration of the shape of a nucleus due to pressure exerted by adjacent nuclei. This phenomenon is often observed in certain types of cancer, such as carcinomas, and is considered a diagnostic feature in some cases.
Overview[edit | edit source]
Nuclear moulding is a characteristic feature of certain types of neoplasia, particularly those of epithelial origin. It is often observed in adenocarcinomas and squamous cell carcinomas, among others. The phenomenon is thought to occur due to the high cell density within these tumors, which results in physical pressure being exerted on the nuclei of individual cells.
Clinical significance[edit | edit source]
The presence of nuclear moulding can be a useful diagnostic feature in the evaluation of suspected neoplasms. It is often used in conjunction with other morphological features, such as nuclear atypia and mitotic activity, to aid in the diagnosis of malignancy. However, it is not specific to cancer and can also be observed in certain benign conditions, such as proliferative breast disease.
See also[edit | edit source]
References[edit | edit source]
| Nuclear moulding Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
