Nuclease
Nuclease is a type of enzyme that is capable of cleaving the phosphodiester bonds which link the nucleotides of nucleic acids. Nucleases are divided into two broad categories: endonucleases and exonucleases.
Function[edit | edit source]
Nucleases play a crucial role in many biological processes, including DNA replication, DNA repair, and apoptosis. They are involved in the maintenance and repair of genetic material, and in the regulation of gene expression.
Types[edit | edit source]
There are two main types of nucleases: endonucleases and exonucleases.
Endonucleases[edit | edit source]
Endonucleases cleave phosphodiester bonds within a nucleic acid chain. They are further classified into restriction endonucleases and non-restriction endonucleases.
Exonucleases[edit | edit source]
Exonucleases remove nucleotides from the ends of DNA or RNA molecules. They are further classified into 3'-5' exonucleases and 5'-3' exonucleases.
Role in Biotechnology[edit | edit source]
Nucleases have a significant role in biotechnology and genetic engineering. They are used in molecular cloning, gene therapy, and CRISPR technology.
See Also[edit | edit source]
References[edit | edit source]
| Nuclease Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
