Nucleoporin 205

From WikiMD's Food, Medicine & Wellness Encyclopedia

Nucleoporin 205 (NUP205) is a protein that in humans is encoded by the NUP205 gene. It is a component of the nuclear pore complex, a structure that regulates the movement of molecules between the nucleus and the cytoplasm.

Function[edit | edit source]

NUP205 is a member of the nucleoporin family. Nucleoporins are proteins that play crucial roles in the nuclear pore complex structure and function. NUP205 is located on the cytoplasmic face of the nuclear pore complex and is involved in the nuclear export of mRNA and proteins.

Clinical significance[edit | edit source]

Mutations in the NUP205 gene have been associated with various diseases. For example, a mutation in this gene has been linked to primary biliary cirrhosis, a chronic disease of the liver. Additionally, NUP205 has been implicated in several types of cancer, including breast cancer and lung cancer.

Research[edit | edit source]

Research on NUP205 is ongoing, with studies focusing on its role in cell division and its potential as a therapeutic target in cancer treatment.

See also[edit | edit source]

References[edit | edit source]



Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD