Nucleoporin 35

Nucleoporin 35 (Nup35) is a protein that in humans is encoded by the NUP35 gene. It is a component of the nuclear pore complex, a structure that regulates the movement of molecules between the nucleus and the cytoplasm in eukaryotic cells.

Function

Nucleoporin 35 is a part of the nuclear pore complex, which is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nup35 is one of the approximately 30 different proteins that make up this complex, and it plays a crucial role in the transport of RNA and proteins across the nuclear envelope.

Structure

The NUP35 gene encodes a protein that is a member of the nucleoporin family. The encoded protein is likely to be a membrane-associated protein, and it is a component of the nuclear pore complex. The NUP35 protein has a molecular weight of approximately 35 kDa, hence its name.

Clinical significance

Mutations in the NUP35 gene have been associated with various diseases, including cancer. Further research is needed to fully understand the role of Nup35 in disease development and progression.

See also

• Nuclear pore
• Nucleoporin
• Nuclear envelope

References

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