Nucleorhabdovirus

From WikiMD's Wellness Encyclopedia

Nucleorhabdovirus is a genus of viruses in the order Mononegavirales, family Rhabdoviridae, and subfamily Sigmavirus. There are currently seven species in this genus including the type species Sonchus yellow net virus. Diseases associated with this genus include: systemic infection, often causing death.

Structure[edit | edit source]

Viruses in Nucleorhabdovirus are enveloped, with bullet shaped geometries. The diameter is around 75 nm, with a length of 180 nm. Genomes are linear, around 11-15kb in length.

Life Cycle[edit | edit source]

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral G glycoproteins to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the negative stranded RNA virus replication model. Negative stranded RNA virus transcription, using polymerase stuttering is the method of transcription. The virus exits the host cell by budding, and tubule-guided viral movement. Plants and insects serve as the natural host. Transmission routes are mechanical, seed borne, and contact.

Species[edit | edit source]

The genus consists of the following species:

References[edit | edit source]

External links[edit | edit source]



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Contributors: Prab R. Tumpati, MD